FootCareDirect Footcare Resource

Injection Treatments

Podiatrists often utilize injections for foot and ankle pain management and wound care. For example, ankle arthritis can be irritating to patients and amenable to either a steroid injection or a regenerative medicine injection.


Regenerative medicine involves the use of stem cells to help the body regenerate organs, tissues, or cells to restore or establish function. In podiatry, regenerative medicine generally applies to damaged tissue, synovial fluid, cartilage, tendons, ligaments, or muscles.

Considerable success can be found utilizing regenerative medicine injections which include anti-inflammatory material, mesenchymal stem cells, and cytokines along with hyaluronic acid. This combination has been providing excellent pain relief and increasing healing potential in arthritis, trauma, and tendon and ligament injuries.

Along with providing steroid and regenerative medicine injections for arthritis and pain management, these injections are also provided to facilitate wound healing in diabetic wounds and others such as crush injuries. The results so far have shown a decrease in healing time by 50%.

Dr. Richard Jacoby discusses the benefits of amniotic stem cell injections

In the past, inflammation and pain have been managed using steroid injections that contain cortisone. While these injections offer anti-inflammatory properties that can effectively reduce inflammation, they don't actually correct the underlying problem. This means that whatever caused the inflammation in the first place, such as plantar fasciitis, continues to cause inflammation after the steroids metabolize. Additionally, because of the risks associated with steroid injections, only a limited number of injections can be given in a certain period of time.

Stem cell injections vary in three primary ways:

  1. They don't contain any steroids, which means there is no risk of potentially damaging cartilage
  2. The injection material has an anti-inflammatory quality as well as ingredients that help lubricate joints
  3. The injection material has potential ability for cell regeneration, which can actually alter the state of the disease rather than simply address symptoms

For these reasons, stem cell injections can be safer and more effective than cortisone injections.

The material does not involve any fetal tissue and is not embryonic. The material used at Extremity Health Centers contains mesenchymal stem cells from consenting donors that have undergone culturing and toxicity testing of the samples by the lab. Amniotic fluid is known as a rich source of stem cells that maintain the capacity to form multiple tissue types. This may contain potential for several clinical applications around the foot and ankle both for wound healing and for joint treatments, along with soft tissue injections.

Laser treatment following stem cell injections?

Laser treatments often are utilized to allow difficult wounds to heal faster as well. When a diabetic patient has either a foot ulcer or a surgical procedure on the foot and ankle, wound healing may be an extremely difficult task.